Ahmed Al-Harrasi

tris‐Schiff Base Derivatives Containing Flurbiprofen as Potential Tyrosinase Inhibitors: Synthesis, In Vitro Evaluation, Molecular Docking, DFT and Dynamics Simulations

ABSTRACT A novel series of tris‐Schiff bases of flurbiprofen has been synthesised via multi‐step reactions, structures were deduced by means of HR‐ESI‐MS, 13C‐ and 1H‐NMR spectroscopy and screened for their in vitro tyrosinase inhibitory potential. All the synthetic derivatives attributed noteworthy inhibition except c...