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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ahmed Ali

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Open access Sep 2026

Vpu protects HIV-infected cells from antibody-dependent cellular phagocytosis by counteracting tetherin.

Tetherin is an interferon-inducible transmembrane protein that inhibits the detachment of enveloped viruses from infected cells. HIV-1 Vpu counteracts this restriction by removing tetherin from sites of virus release. Accordingly, Vpu mutations that disrupt tetherin antagonism increase Env accumulation on the surface o...

Brian J. Snow, Nida K. Keles, Ahmed Ali et al. · 0 citations

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