Intravenous ketamine compared to intranasal esketamine for treatment-resistant major depressive disorder. a meta-analysis of randomized controlled trials for efficacy and pharmacovigilance outcomes
Treatment-resistant depression (TRD) represents a significant therapeutic challenge in psychiatry. While both intravenous (IV) ketamine and intranasal (IN) esketamine have been raised as promising medical treatments for TRD, their comparative efficacy and safety profiles remain unclear. This meta-analysis aimed to eval...