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Author

Ahmed F. El-Sayed

Independent Researcher

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Open access Oct 2026

Nano route with DFT, docking studies, ADMET, and SAR of a pyran-functionalized pyrimidine scaffold as a potent Rhizoctonia solani

Numerous plant infections known as phytopathogenic fungi are responsible for a broad range of agricultural illnesses. Recent research focuses on developing, synthesizing, and evaluating pyran-linked pyrimidine hybrids as potential antifungals. In this study, the target hybrids of the pyran-functionalized pyrimidine sca...

B. Farag, G. El-Bana, H. A. Abd El-Lateef et al. · 0 citations
Aug 2026

Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as promising antioxidant and antimicrobial agents: Synthesis, antibiofilm, DFT calculations, molecular docking, ADMET analysis, and MD simulations.

The escalating threat of antimicrobial resistance necessitates the discovery of novel therapeutic scaffolds with distinct mechanisms of action. A novel series of [1,2,4]triazolo[1,5-a]pyrimidine derivatives (FNT01-12) featuring various aromatic substitutions at positions 5 and 7 was designed, synthesized, and evaluated...

Farid M. Sroor, Ahmed F. El-Sayed · 0 citations

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