Bis-Triazole-Containing Heterocycles: Synthesis, Pharmacokinetic Prediction, Molecular Modeling, and Antimicrobial Activity Evaluation
Abstract The 1,2,4-triazole nucleus is a privileged scaffold in medicinal chemistry, as it is present in many clinically approved antifungal, anticancer and antiviral agents. However, the development of new triazole-based derivatives with better potency and safety profiles is demanded due to the emergence of antimicrob...