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Author

Ahmed Sharara

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Sep 2026

Pharmacological modulation of GLI signaling promotes human iPSC-derived cardiomyocyte maturation via PGC1α-associated mitochondrial programs.

GLI signaling is identified as a modulatory pathway influencing the structural, electrophysiological, and mitochondrial gene programs associated with hiPSC-CM maturation and GLI modulation is highlighted as a strategy to enhance the physiological relevance of hiPSC-derived cardiac models.

M. Shameem, Ahmed Sharara, Ina Xhelilaj et al. · 0 citations

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