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Ahyeon Son

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Open access Jul 2026

Identification of the SARS-CoV-2 genome packaging signal in the nsp12-coding region

A SARS-CoV-2 packaging signal is identified within the nsp12 coding region and shows that the nucleocapsid protein mediates selective genome packaging through its C-terminal domain, establishing the mechanistic basis for SARS-CoV-2 genome packaging and offer a potential antiviral target.

Youngran Park, Jongmin Lim, Hyeonggon Cho et al. · 0 citations