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Sep 2026

High-level surfactin production by Bacillus subtilis through integrated metabolic engineering and bioprocess optimization.

Surfactin is a cyclic lipopeptide biosurfactant produced by Bacillus species and has considerable potential as a sustainable alternative to petroleum-derived surfactants. However, efficient surfactin production remains constrained by the limited productivity of native strains, inadequate precursor supply and suboptimal...

Ai Chen, Yu-Kang Xie, Min Liu et al. · 0 citations
Sep 2026

Engineering of central metabolism for high-yield 1,3-propanediol production using co-substrates by Klebsiella pneumoniae.

1,3-Propanediol is a versatile C3 diol serving as a key building block used in various industries. Klebsiella pneumoniae represents an attractive microbial chassis for 1,3-PDO production due to its endogenous 1,3-PDO and Vitamin B₁₂ biosynthetic pathways. However, low carbon flux and by-product formation remain bottlen...

Shao-Qi Sun, Ai Chen, Wen-Qi Wang et al. · 0 citations

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