Dynamic GelMA/Oxidized Hyaluronic Acid Hydrogels Enable Acid-Accelerated Localized Delivery of Photothermal Melatonin-Derived Carbon Dots for Infected Bone Repair.
Infected bone defects remain difficult to reconstruct because bacterial persistence, acidic stress, excessive reactive oxygen species (ROS), inflammatory dysregulation, and impaired osteogenesis reinforce one another. Here, sulfur-doped melatonin carbon dots (DM-CDs) were synthesized from melatonin and d-cysteine and i...