Author

Ai-Li He

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Open access Sep 2026

IRF1-mediated thioredoxin (TXN) protects multiple myeloma cells from ferroptosis through remodeling of PUFA-containing phospholipids

Thioredoxin (TXN), a central redox regulator, is identified as a ferroptosis suppressor associated with poor prognosis in MM patients and the IRF1-TXN axis is established as a potential therapeutic target for overcoming ferroptosis resistance and improving MM treatment outcomes.

Jia-Xi Liu, Ji-Yu Miao, Yang Lv et al. · Cell Death & Disease · 0 citations

Open access Jul 2026

Homoharringtonine in combination with Tanshinone IIA suppresses the progression of lymphoma cells by downregulating the Akt/MMP signaling pathway

HHT and Tan IIA combined therapy synergistically suppressed lymphoma progression by downregulating the Akt/MMP signaling pathway, suggesting their use in treating lymphomas.

Yanping Zhang, Jian Yin, Rui Liu et al. · Cytotechnology (Dordrecht) · 0 citations