Ai-Lun Li

Advancing neurofibromatosis research: a comparative review of animal models and their utility in dissecting the tumor microenvironment

Neurofibromatosis is a genetic disorder characterized by nervous system tumors arising primarily from NF1 or NF2 mutations. Given the complexity of the genetic background and heterogeneity of associated tumor phenotypes in neurofibromatosis, mechanistic investigations rely heavily on experimental animal models. Human t...