The long-standing challenge of seasonal influenza vaccines providing poor protection is attributed to the rapid and continuous evolution of the virus. In theory, the recommendation of vaccine strain is to predict the dominant strain with best fitness in the upcoming season. Here, we develop FutureFlu, a biologically-gr...
Lu-Yao Qin, Meng-Yi Zhang, Xiao-Yuan Liu et al.· bioRxiv· 0 citations
OBJECTIVE
To investigate nosocomial non-vector-borne transmission of Dabie bandavirus (DBV) using clinical, epidemiological, virological, and genomic evidence.
METHODS
We conducted a comprehensive multidisciplinary study of six patients within a hospital setting, integrating detailed epidemiological contact tracing,...
Shan Hong, Kai Li, Jing-Qi Yang et al.· International Journal of Inf...· 0 citations
An integrative host-directed drug discovery framework combining functional genomics and pharmacotranscriptomics is developed, providing a systematic and scalable strategy for discovering antivirals that are less susceptible to resistance and potentially applicable to other rapidly evolving pathogens.
Jianfa Qiu, Xuecong Xing, Jing-Feng Wang et al.· iScience· 0 citations
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