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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Aida Mestre-Farrera

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Open access Aug 2026

Emerging roles of ATR beyond DNA damage repair: orchestrating transcriptional reprogramming during epithelial-to-mesenchymal transition

Two pivotal studies published in this issue of JCI provide key insights into how ATR intersects with EMT transcriptional reprogramming and uncovered a role for ATR in ECM stiffness–induced EMT, which was associated with an immunosuppressive tumor microenvironment.

Aida Mestre-Farrera, Zhimin Hu, Jing Yang · 0 citations

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