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Author

Aijun Wang

2 papers indexed here

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Open access Sep 2026

Charge-switching ionizable lipids lower the toxicity of lipid nanoparticles.

Lipid nanoparticles (LNPs) have great potential as nucleic acid delivery vehicles; however, they trigger the production of inflammatory cytokines, which limits their medical applications. Developing non-inflammatory LNPs is challenging because the LNP's ionizable lipid and the process of endosomal disruption are the ma...

Deng-Pan Liang, Ya-Lin Qi, He-Song Han et al. · 0 citations
Open access Aug 2026

Scalable generation of hematopoietic stem cell-engineered off-the-shelf mono-specific cytotoxic T cells targeting solid tumors

HSPC-derived AlloESO-T cells are established as an off-the-shelf, mono-specific cytotoxic T cell therapy with scalable manufacturing, enhanced efficacy, and improved safety, which support broad applicability of AlloESO-T cells across solid tumors.

Yi-Chen Zhu, Jia-Ji Yu, Y. J. Kim et al. · 0 citations

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