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Aishwarya Saha

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Review Aug 2026

Deciphering the role of sirtuins in cancer immunoregulation through molecular cross-talk and docking-based interaction

The modulatory role of Sirtuins in FOXP3 expression and Treg differentiation is reviewed, providing insight into their contribution to tumor immunosuppression and integrating network-based analysis identified miR-34a as a central regulator and validated the miRNA-Transcription Factor-Sirtuin axis as a viable framework for cancer therapeutic targeting.

Aishwarya Saha, Sriparna De, Sreya Chattopadhyay et al. · 0 citations