Molecular mechanisms of Polyendocrine Metabolic Ovarian Syndrome and identification of novel druggable targets for drug discovery and repositioning.
Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a heterogeneous disorder that mainly affects women of reproductive age. Genetic predisposition, insulin resistance, androgen excess, inflammation, mitochondrial dysfunction, and changes in gut microbial composition were notable contributors to the prognosis of PMOS. Se...