Author

Alan Costello

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Open access Jul 2026

Structural adaptations for enhanced translation kinetics in evolved ribosomes

This work structurally characterize chimeric ribosomes derived from Escherichia coli, Pseudomonas aeruginosa, and Vibrio cholerae using cryo-electron microscopy and uncover a potential relationship between 16S ribosomal RNA (rRNA) stability and translation efficiency, providing new insights into rRNA structural malleability.

Tushar Raskar, Alan Costello, A. Badran et al. · Nucleic Acids Research · 0 citations