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Author

Alberto Guarnieri

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Review Sep 2026

The mechanisms and mechanics of aging.

Aging tissues paradoxically stiffen while losing mechanical resilience, becoming fragile, poorly regenerative and chronically inflamed. We review evidence that these phenotypes emerge from progressive failure of mechanotransduction across a mechanically integrated axis linking extracellular matrix (ECM) architecture, i...

Anastasia Zhurikhina, Maia Kirkegaard, Alberto Guarnieri et al. · 0 citations

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