Aleena A. Saidova

Tau phosphorylation in Alzheimer’s disease: emerging mechanisms, network interactions, and therapeutic implications

While amyloid-β (Aβ) has historically dominated the research landscape of Alzheimer’s disease (AD), the limited clinical success of Aβ-centric therapies has redirected focus toward tau pathology, which correlates more robustly with cognitive deterioration and synaptic dysfunction. Transcending the traditional linear...