A systematic review to evaluate effect modification by molecular endotype across randomized ARDS trials and assess credibility of reported subgroup effects exposed current knowledge gaps in how subgroups are defined and inform future clinical practice guideline recommendations.
L. V. Van Nynatten, Chris McChesney, Mujtaba M. Basharat et al.· Annals of the American Thora...· 0 citations
Critical illness syndromes, such as sepsis and acute respiratory distress syndrome (ARDS), are characterized by substantial clinical heterogeneity and remain major causes of morbidity and mortality worldwide. Increasing evidence suggests that genetic variation contributes to susceptibility, disease severity, and clinic...
Jonathan J. Moroniti, Poorna Manappurathu Rameshchandran, Meng-Qi Guo et al.· Frontiers in Pharmacology· 0 citations
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