Aleksandra L. Burmistrova

CONTRIBUTION OF TOLL-LIKE RECEPTORS AND CYTOKINE GENES POLYMORPHISMS TO THE RISK OF DEVELOPING ULCERATIVE COLITIS

Introduction. Inflammatory bowel disease (IBD), the incidence of which continues to rise in urbanized populations, remains a common problem. Over 260 genetic loci associated with IBD have been identified, many of which are involved in immune sensing and signaling pathways [3]. Ulcerative colitis (UC) is a multifactoria...