The immune response of our body, whether it is directed to infective agents, allergens, or tumors, should support our recovery but can also be dangerous if dysregulated. There are molecular systems that have the role of tuning the immune response, such as activating and inhibitory receptors and co-stimulatory molecules...
Chiara Rosa Maria Uras, Martina Taglieri, Linda Di Gregorio et al.· Biomolecules· 0 citations
It is suggested that KIR3DL01+ NK cells contribute to the inhibition of SIV replication during chronic infection, and the feasibility of AAV-vectored antibody delivery for long-term, perhaps indefinite depletion of a lymphocyte subset in a nonhuman primate model is demonstrated.
Kjell Sandstrom, Grace N. Hagedorn, Sean C Robinson et al.· PLoS Pathogens· 0 citations
Examination is given to how NK-directed and NK-complementary approaches, including cytokine-based activation, NK-cell engagers, adoptive NK-cell transfer, chimeric antigen receptor natural killer cell (CAR-NK) platforms, and their integration with immune checkpoint blockade, may help address resistance in EC.
Alessandro Poggi, V. Bruno, Anna Di Spirito et al.· Frontiers in Immunology· 0 citations
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