Author

Alessia Floramo

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Open access Sep 2026

Bioactivated Glucoraphanin Exerts a Potential Protective Effect in an In Vitro Model of Parkinson’s Disease: A Transcriptomic Study

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Oxidative stress is involved in disease pathogenesis, with the consequent damage to DNA. Nowadays, phytocompounds attract much interest for their capacity to modulate some of the pathogenic mechanism...

A. Gugliandolo, Claudia Muscarà, Alessia Floramo et al. · International Journal of Mol... · 0 citations

Review Open access Aug 2026

Decoding Synaptic Diversity: Molecular Architectures, Phase Transitions, and Shared Postsynaptic Failure in Alzheimer’s and Parkinson’s Disease

This review dissects the hierarchical organization of the synaptome, arguing that synaptic decay is not a generic process of attrition but a specific collapse of subsynaptic domains (SSDs) and trans-synaptic nanocolumns, considered here within the framework of the tetrapartite synapse.

G. Cipriano, Ivan Anchesi, Alessia Floramo et al. · Cells · 0 citations