Author

Alessio Ciulli

h-index 4 View on Semantic Scholar

We have 2 of 23 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Fitness criteria for PROTACs as chemical probes: principles and applications.

Proteolysis-targeting chimeras (PROTACs) have emerged as a powerful class of chemical probes that degrade rather than inhibit target proteins, thus expanding the tools for studying protein function in cells. PROTACs trigger catalytic and sub-stoichiometric degradation of the target protein in contrast with stoichiometr...

M. Sturbaut, Alessio Ciulli · Essays in Biochemistry · 0 citations

Open access Jul 2026

Induced ubiquitination of the partially disordered estrogen receptor alpha via a 14-3-3 directed molecular glue-PROTAC

A molecular glue-stabilizer and PROTAC strategies are combined to enable ubiquitination of the 14-3-3/estrogen receptor α complex, revealing cooperative linker-dependent activity and a structural basis for targeted E3 ligase recruitment.

Carlo J. A. Verhoef, Charlotte Crowe, M. Nakasone et al. · Nature Communications · 0 citations