Author

Alexander Ciupa

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Review Open access Aug 2026

Three privileged scaffolds, one pipeline: chalcones, pyrazolines and pyrazoles in drug discovery and fluorescent sensing

This review examines leading examples from 1990 to 2025 across all three scaffold classes, with particular emphasis on the most promising applications of this pipeline: anti-cancer, anti-inflammatory, anti-viral, and fluorescent sensing applications.

Alexander Ciupa · RSC Medicinal Chemistry · 0 citations

Open access Sep 2026

Electrospun poly(vinyl alcohol) nanofibers loaded with quaternary ammonium compounds for localized eradication of periodontal biofilms

Periodontitis is driven by polymicrobial biofilms and remains difficult to treat using systemic antibiotics, which fail to achieve therapeutic concentrations within periodontal pockets. In this study, we report on the fabrication of electrospun poly(vinyl alcohol) (PVA) nanofibers incorporating quaternary ammonium comp...

Ting Chen, Nicola Kelly, P. L. Oseliero et al. · Materials Advances · 0 citations