Author

Alexander Jaworski

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Open access Oct 2026

A genetic screen for suppressors of neuron degeneration in a C. elegans sod-1G85R model of Amyotrophic Lateral Sclerosis.

Genetic variants in superoxide dismutase 1 (SOD1) cause the progressive neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS). Treatments for this disease are limited, and the unique vulnerability of cholinergic and glutamatergic motor neurons to degeneration seen in ALS patients is not clearly understood. Iden...

Katherine S. Yanagi, Alexander T. Lin-Moore, Nijpawi C. Gordon et al. · G3 · 0 citations

Open access Sep 2026

Gene expression programs underlying spinal commissural neuron differentiation and axon growth across the midline

Commissural neurons in the spinal cord project axons across the midline to fulfill various critical functions in somatosensory information processing and left-right coordination of motor output. These neurons have long served as a powerful model system for axon pathfinding, driving the discovery of molecules and mechan...

Jane R. Abolafia, Hanna Hameedy, Lakshmi Prakash et al. · Proceedings of the National... · 0 citations