Sep 2026
LNP-formulated dbDNA™ vaccines elicit durable humoral and cellular immunity with distinct kinetics to mRNA in non-human primates.
Nucleic acid vaccines offer rapid and flexible platforms for addressing infectious diseases but achieving durable and balanced immunity remains a challenge. We evaluated a closed linear synthetic Doggybone™ DNA vaccine (dbDNA™) encoding influenza A/California/07/2009 hemagglutinin across delivery platforms and preclini...
Helen Horton, Robert F. Cunliffe, Sungwon Kim et al.
· Molecular Therapy · 0 citations