Open access
Jul 2026
Genome-wide multi-layered epigenomic profiling across human aging
Deep whole-genome bisulfite sequencing data from blood samples of 120 healthy donors revealed only limited association between age-associated epigenetic alterations in DNA methylation, chromatin accessibility, and histone modifications, arguing against a broadly coordinated remodeling of the aging epigenome.
M. Steiger, René Krüger, Mina Shaigan et al.
· bioRxiv · 0 citations