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Author

Alexander Muir

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Sep 2026

Abstract A019: Tumor Nutrient Stress Regulates Cancer-associated Fibroblast Heterogeneity

Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer type with a 5-year survival rate of only 13%. PDAC is unique in that up to 90% of the tumor bulk is comprised of a dense desmoplastic stroma. Enriched within PDAC’s extensive stroma are cancer-associated fibroblasts (CAFs). CAFs orchestrate tumor progression...

Marta R. Storl-Desmond, Nicole Liu, K. Forti et al. · 0 citations

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