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Alexandra A. Dalina

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Open access Sep 2026

The p53-Associated Regulation of ATF4 mRNA Expression Involves p21 and p130 in a Stress-Dependent Manner

P53 activation is associated with reduced ATF4 mRNA expression under basal conditions and during selected metabolic stresses, including mitochondrial dysfunction, and it is suggested that p53, p21, and p130 may influence the ATF4-dependent branch of the ISR during cellular stress.

Alexandra A. Dalina, Maria Shilyaeva, I. Kovaleva et al. · 0 citations

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