Open access
Aug 2026
RAD51 proximity mapping reveals spatial constraints on homology search during DNA double-stranded break repair.
DNA double-stranded breaks (DSBs) are toxic events that can be reversed without genetic information loss by homology-directed repair (HDR), wherein information is copied from an intact template molecule. Finding a correct template within millions to billions of other DNA bases is termed homology search and is mediated...
Charles D. Yeh, Lilly van de Venn, Susanne Kreutzer et al.
· Cell Reports · 0 citations