Author

Alexandra Serrato

2 papers indexed here

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Open access Sep 2026

Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced weight gain in female mice

Most antipsychotic drugs (APDs) cause hyperphagia and weight gain, yet the neural mechanisms underlying these metabolic side effects remain elusive, in part due to difficulties in modeling them in rodents. Here, we establish a mouse model that recapitulates clozapine-induced metabolic syndrome, enabling mechanistic inv...

Li Li, Ciria C. Hernandez, L. E. Gimenez et al. · Nature Communications · 0 citations

Open access Aug 2026

Complementary Models of Cardiometabolic Stress Reveal Conserved Molecular Programs Driving Cardiac Remodeling

Background Cardiometabolic diseases frequently involve concurrent cardiovascular and hepatic dysfunction, yet the conserved molecular mechanisms underlying these systemic responses remain poorly defined. Objectives To identify conserved molecular responses across complementary manifestations of cardiometabolic stress a...

Maaria Saeed, Hyun-Jung Jung, Bo Ryung Lee et al. · bioRxiv · 0 citations