Alexey V. Emelyanov

Synucleins deficiency alter dopamine- and glutamate-induced calcium signal in neurons and astrocytes.

Proteins α-, β-, and γ-synuclein in brain distributed predominantly in presynaptic terminals suggesting their role in regulating neurotransmitter release and signal transduction. Misfolded α-synuclein is involved in the pathology of Parkinson's disease which is characterized by the loss of dopaminergic neurons and the...