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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Alexi Nott

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2 papers indexed here

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Open access Sep 2026

Cell type-specific histone acetylation landscape in Alzheimer’s disease reveals a putative role of MITF in microglia

Alzheimer’s disease (AD) is characterised by aberrant amyloid beta and tau aggregation, neuroinflammation, demyelination and neurodegeneration, which have been linked to changes in cell-specific gene expression signatures. Among the mechanisms driving cell-type-specific transcriptional changes, histone acetylation play...

Charbel Gergian, Paulina Urbanaviciute, Philippa M. Wells et al. · 0 citations
Open access Jul 2026

A roadmap for enriching rare cell populations from human post-mortem brain, demonstrated by 100% microglial purity

A generalisable roadmap for developing fluorescence-activated nuclear sorting protocols for rare cell populations in human brain is presented, reaching 100% purity in cortex and 98% in cerebellum, with the cortex sort simultaneously yielding astrocytes at 93% purity.

Isidora Gocmanac, Hiranyamaya Dash, M. Weinert et al. · 0 citations

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