Multiple sclerosis (MS) is an immune-mediated disease characterized by inflammatory demyelination and axonal degeneration in the central nervous system (CNS) and has been linked to viral infections. Theiler’s murine encephalomyelitis virus (TMEV) infection in SJL/J mice has been widely used as a viral model of MS, sinc...
F. Sato, Alfredo A. Hinay, Seiichi Omura et al.· Cells· 0 citations
Viral infection of the central nervous system (CNS) is increasingly linked to neurodegenerative disease, yet the metabolic programs that shape antiviral immunity and neuroinflammation remain poorly defined. Nicotinamide adenine dinucleotide (NAD) regulates mitochondrial function and immune signaling, and supplement...
Cong Thanh Nguyen, F. Sato, Seiichi Omura et al.· Scientific Reports· 0 citations
Dengue remains a major public health concern in the Philippines, where routine surveillance systems classify reported cases as suspected, probable or confirmed. Although these classifications are widely used to monitor disease burden, their influence on the interpretation of long-term epidemiological trends and mor...
Alfredo A. Hinay, Jennifer Ashley H. Reyes, George Carr G. Plaza· Frontiers in Tropical Diseas...· 0 citations
Leptospirosis remains a significant public health concern in the Philippines, particularly in urban tropical settings where environmental and climatic conditions favor disease transmission. This study examined temporal trends and factors associated with human leptospirosis in Davao City, Philippines, using surveillance...
Rachelle Laine Durang, Rvin John T. Servillon, Aprilyn F. Francisco-Breva et al.· Acta Microbiologica Hellenic...· 0 citations
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