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Author

Alfredo A. Hinay

4 papers indexed here

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Open access Sep 2026

IgA Deficiency Exacerbates an Animal Model of Multiple Sclerosis Induced with Theiler’s Virus

Multiple sclerosis (MS) is an immune-mediated disease characterized by inflammatory demyelination and axonal degeneration in the central nervous system (CNS) and has been linked to viral infections. Theiler’s murine encephalomyelitis virus (TMEV) infection in SJL/J mice has been widely used as a viral model of MS, sinc...

F. Sato, Alfredo A. Hinay, Seiichi Omura et al. · 0 citations
Open access Aug 2026

Altered NAD metabolism during CNS viral infection and modest immunometabolic effects of NMN in different contexts

Viral infection of the central nervous system (CNS) is increasingly linked to neurodegenerative disease, yet the metabolic programs that shape antiviral immunity and neuroinflammation remain poorly defined. Nicotinamide adenine dinucleotide (NAD) regulates mitochondrial function and immune signaling, and supplement...

Cong Thanh Nguyen, F. Sato, Seiichi Omura et al. · 0 citations
Open access Sep 2026

Temporal trends in dengue incidence and mortality across surveillance case classifications: a 13-year analysis from Davao City, Philippines

Dengue remains a major public health concern in the Philippines, where routine surveillance systems classify reported cases as suspected, probable or confirmed. Although these classifications are widely used to monitor disease burden, their influence on the interpretation of long-term epidemiological trends and mor...

Alfredo A. Hinay, Jennifer Ashley H. Reyes, George Carr G. Plaza · 0 citations
Open access Jul 2026

Temporal Trends and Factors Associated with Human Leptospirosis in Davao City, Philippines: An 11-Year Surveillance Analysis (2015–2025)

Leptospirosis remains a significant public health concern in the Philippines, particularly in urban tropical settings where environmental and climatic conditions favor disease transmission. This study examined temporal trends and factors associated with human leptospirosis in Davao City, Philippines, using surveillance...

Rachelle Laine Durang, Rvin John T. Servillon, Aprilyn F. Francisco-Breva et al. · 0 citations

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