Review
Open access
Sep 2026
Development and Evaluation of Physiologically Based Pharmacokinetic (PBPK) Models of Metoclopramide Across the Lifespan: Translation from Adults to Infants
Background: Physiologically based pharmacokinetic (PBPK) modeling is an established approach used in recent years for estimating drug disposition in challenging clinical scenarios where in vivo studies are difficult to perform. Metoclopramide is a benzamide derivative, widely indicated for its antiemetic and prokinetic...
Iqra Shahzad, Ammara Zamir, M. Rasool et al.
· Pharmaceuticals · 0 citations