Author

Alina Baum

2 papers indexed here

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Open access Oct 2026

Maftivimab monotherapy is effective in a non-human primate model of Bundibugyo virus disease

It is demonstrated that Maftivimab neutralizes BDBV, binds to its epitope on BDBV GP and is efficacious in treating established BDBV disease in the macaque model, and the data support its evaluation in clinical trials during the ongoing or future outbreak.

Meike Dittmann, Dylan M. Johnson, M. Rapp et al. · bioRxiv · 0 citations

Clinical trial Open access Sep 2026

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults

Abstract REGN17092, a fully human immunoglobulin (Ig) G1 antibody with M252Y/S254T/T256E (YTE) modification in the Fc portion, was assessed in a first‐in‐human study (ClinicalTrials.gov, NCT05923424). REGN17092 was designed to target the severe acute respiratory coronavirus 2 (SARS‐CoV‐2) S protein. However, due to the...

María Rosario, J. D. de Hoon, F. Isa et al. · Clinical pharmacology in dru... · 0 citations