Evaluation of PIK3CA, AKT1, and mTOR Genes Polymorphisms in a Sample of Iranian Women with Breast Cancer Compared with Healthy Women.
OBJECTIVE Breast cancer (BC) is the most common cancer among women globally, with Iranian women showing an earlier onset compared to those in Western countries. Genetic variations in the PI3K/AKT/mTOR signaling pathway have been implicated in cancer susceptibility, but limited studies exist on the association of these...