Author

Allan Jordan

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Aug 2026

Beyond Cytotoxic Payloads for Antibody Drug Conjugates─A Medicinal Chemistry Perspective

Observations around LogD, pKa, permeability, permeability, efflux, and metabolic stability are discussed and design rules and guidelines for the optimization of next-generation ADC payloads are suggested.

Allan Jordan, S. Best, Joshua Greally · Bioconjugate chemistry · 0 citations