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Author

Allison D. Ebert

2 papers indexed here

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Open access Oct 2026

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology.

The dual treatment paradigm using SMN1 gene therapy combined with forskolin treatment to stimulate actin dynamics via increasing cyclic adenosine monophosphate levels resulted in increased branching and filopodia density of SMA astrocytes, and improved synapse formation and function of SMA motor neurons.

Emily Welby, Xiao-Jie Liu, Melinda Wojtkiewicz et al. · 0 citations
Review Open access Sep 2026

The Role of the Mammalian Target of Rapamycin in Microglial Phenotypic Polarization

Highlights What are the main findings? mTOR signaling regulates microglial phenotypic plasticity by coordinating many cellular processes including metabolic reprogramming, inflammatory mediator production, and cytoskeletal remodeling. mTORC1 generally amplifies pro-inflammatory microglial responses, whereas mTORC2 appe...

Kaitlyn J. Partridge, Allison D. Ebert · 0 citations

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