Allison M. Kee

RNA degradation by ribonuclease T2 is required for phosphate homeostasis in S. cerevisiae.

Phosphate is a critical building block for key biomolecules including ATP, DNA, RNA, and phospholipids. Consequently, cells monitor phosphate levels and acquire phosphate when intracellular levels become low. Here we demonstrate an unanticipated connection between the enzymatic activity of the S. cerevisiae RNase T2 or...