Open access
Aug 2026
Trex-QTL: A mixture-model for identification of genetic effects with global effects on molecular phenotypes
While thousands of cis expression quantitative trait loci (cis-eQTLs) have been reliably identified, detecting trans-eQTL effects has proven to be challenging due to insufficient statistical power, lack of comparable tissues and cohorts, and low reproducibility across studies. Here, we present Trex-QTL, a novel trans-e...
Cynthia Wu, Andrey V. Bzikadze, Tian-Yao Xu et al.
· bioRxiv · 0 citations