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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Álvaro Curiel-García

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Sep 2026

Abstract B025: A spatial proximity-weighted algorithm (SPAN) defines reproducible tumor niches and a persister ecosystem underlying acquired resistance to pan-RAS inhibition in PDAC

Spatial transcriptomics extends single-cell analysis of the tumor microenvironment into a mappable ecosystem by resolving gene expression in situ. Within it, cells assemble into recurrent multicellular niches whose spatial organization shapes tumor progression, immune evasion, and therapy response and resistance. Yet...

Álvaro Curiel-García, M. Franchini, L. Tomassoni et al. · 0 citations
Open access Aug 2026

Developmental and MAPK-responsive transcription factors regulate distinct malignant cell states and associated genetic dependencies in pancreatic cancer

The authors apply ARACNe and metaVIPER to published scRNA-seq datasets to characterize pancreatic cancer subtypes, identifying six distinct cell states as well as their mechanistic determinants.

P. Laise, Mikko M. Turunen, Álvaro Curiel-García et al. · 1 citation

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