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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Álvaro Mourenza

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Review Open access Aug 2026

Fighting the invader: strategies against intracellular bacteria

It is argued that integrating pathogen- and host-targeted strategies within a design-build-test-learn cycle, supported by computational modelling and careful attention to safety and pharmacokinetics, offers a route to engineer eradication of intracellular reservoirs, extend antibiotic lifespan and accelerate translatio...

Blanca Lorente-Torres, Pablo Castañera, Jesús Llano-Verdeja et al. · 0 citations
Open access Jul 2026

Design of a cyclic peptide targeting intracellular Staphylococcus aureus

Findings identify cyclotide grafting as a strategy to improve peptide stability and intracellular delivery, and support MCo-KTR2 as a scaffold for further optimization against intracellular MRSA infections.

Álvaro Mourenza, Jesús Llano-Verdeja, Pablo Castañera et al. · 0 citations

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