Author

Alvin Farrel

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Open access Sep 2026

Proteogenomic analysis of pediatric and AYA high-grade glioma reveals age-dependent biology, female-male differences, and kinase targets.

High-grade gliomas (HGGs) in children and adolescents and young adults (AYA) exhibit distinct biology across the neurodevelopmental spectrum. To dissect tumor-intrinsic molecular characteristics independent of developmental variation, we perform comprehensive proteogenomic analyses of tumors from 112 HGG patients aged...

N. Tignor, M. Koptyra, Shrabanti Chowdhury et al. · Cell Reports Medicine · 0 citations

Open access Jul 2026

HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors 2258016

HLA-Shuttle restores antigen presentation in immunologically cold tumor cells, facilitating identification of TAAs with favorable therapeutic potential and identifying multiple novel tumor associated antigens (TAAs) from both known and novel cancer immunotherapy targets.

Daniel Hwang, Molly C. Erdman, Santosh Adhikari et al. · Journal of Immunology · 0 citations