Alvīne Helēna Janševska

Polygenic risk for type 2 diabetes modulates gut microbiome associations across metabolic health traits

In this study, we integrated phenotype data, genotyping, and gut metagenomic data to investigate how genetic predisposition to T2D interacts with the gut microbiome, as well as attenuating lifestyle factors, across metabolic health traits in a cohort of 821 individuals of European ancestry. We evaluated increased B...