Open access
Aug 2026
The CD70/CD27 Axis in Tyrosine Kinase Inhibitor-Treated Chronic Phase Chronic Myeloid Leukemia Cells Is Not an Achilles Heel
The blockade of the CD70/CD27 axis in combination with TKIs did not result in greater LSC elimination than with nilotinib as a single agent in CP CML models, but there was an observed reduction in CD70+ cells with combination treatment.
Jennifer E. Cassels, M. Drotar, Alyson MacNeil et al.
· Hematology Reports · 0 citations