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Author

Amanda Wicki

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Open access Oct 2026

Chemotherapy enhances cancer vaccine efficacy and expands stem-like TCF1+CD8+ T cells.

Therapeutic cancer vaccines are increasingly tested in clinical settings alongside standard-of-care treatments that often include chemotherapy, yet whether chemotherapy synergizes with cancer vaccines remains unclear. Here, we tested heterologous prime-boost viral vector vaccines in combination with various chemotherap...

Laurine Noblecourt, Amanda Wicki, Ashwin K. Jainarayanan et al. · 0 citations
Open access Sep 2026

Thymic age and peripheral residence time determine antitumor competence of CD8+ T cells.

These findings establish developmental imprinting as an important determinant of CD8+ T cell heterogeneity and identify CXCR3+IL-18Rα+ CD8+ T cells as key effectors for antitumor immunity.

Yuan-Qin Yang, Yun-Yi Wang, Amanda Wicki et al. · 0 citations

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