Author

Amel S. Younes

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Sep 2026

Bis-thiosemicarbazone derivative as starting agent for synthesis of anti-breast cancer agents and targeting PIM-1 kinase.

Compound 15c represents a promising PIM-1 kinase inhibitor with potent antiproliferative and pro-apoptotic activities, supporting its potential as a candidate for breast cancer treatment.

Alaa M. Abu Alnjaa, Jihan Qurban, E. Abbas et al. · Future Medicinal Chemistry · 0 citations

Sep 2026

EGFR kinase inhibitors from novel thiazole derivatives: synthesis, anticolon cancer, docking, and ADME studies.

Compound 4j represents a promising lead candidate for the development of novel EGFR-targeted anticancer agents and demonstrated remarkable potency with an IC50 value of 0.27 µM.

Amani M. R. Alsaedi, Alaa M. Abu Alnjaa, Amel S. Younes et al. · Future Medicinal Chemistry · 0 citations