Primary large-cell neuroendocrine carcinoma of the submandibular gland arising from a long-standing benign tumor: case report
Background: Large-cell neuroendocrine carcinoma (LCNEC) is an aggressive malignancy that commonly arises in the lungs. Primary salivary gland involvement is exceptional, presenting a major diagnostic challenge in differentiating it from metastatic pulmonary disease. Case presentation: A 62-year-old man presented with a...